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77 Results Found for “cerebral haemorrhage”
Acute ischaemic stroke management Recent randomized controlled trials (RCTs) comparing bridging intravenous thrombolysis (IVT) with tissue plasminogen activator (tPA) to direct endovascular treatment (EVT) for large-vessel occlusion (LVO) strokes within 4.5 hours of onset have failed to show inferiority of direct ...
Dr Ellis van Etten, vascular neurologist and clinical scientist at Leiden University Medical Center, specializes in cerebral amyloid angiopathy and other types of cerebral small vessel disease. With early research training at J. Philip Kistler Stroke Research Center at Massachusetts General Hospital, and a PhD on cerebral amyloid angiopathy at Leiden University, she is now actively contributing to international research, including participation in a multicentre phase II trial.
Epilepsy affects approximately 1% of the global population, with one-third of patients remaining refractory to medical therapy.1Â Drug-resistant epilepsy (DRE), defined as the failure of two appropriately chosen antiseizure medications (ASMs) to achieve seizure freedom, poses significant risks, including injury and ...
As a touchNEUROLOGY Future Leader 2025, Dr Antonio Ciacciarelli shares what drew him to neurology, the lasting impact of mentorship, and why recent advances in stroke care are redefining outcomes. He reflects on the privilege of inspiring others, and the promise of neuroprotection as the next frontier in vascular neurology.
The prevalence of unruptured intracranial aneurysms (IAs) is approximately 3% of the population, with incidence on the rise due to the increased utilization of neuro-imaging for diverse objectives.1,2 The average risk of rupture for unruptured IA is estimated to vary from 0.3% ...
Diabetic striatopathy (DS) is a rare hyperglycaemic condition associated with one or both of the following criteria: (1) acute-onset chorea–ballism (random, flowing and nonsuppressible involuntary movements) and (2) striatal hyperdensity on computed tomography (CT) scan or T1-weighted magnetic resonance imaging (...
A study published in The Lancet Neurology reveals a troubling stagnation in the progress against stroke burden worldwide, with incidence rates failing to decline significantly since 2015. This analysis of the Global Burden of Disease (GBD) Study 2021 shows that the absolute numbers of strokes, related deaths and disability-adjusted life years (DALYs) have all risen considerably from 1990 to 2021, despite earlier global efforts aimed at reducing stroke mortality
Case study Patient information A 42-year-old woman presented in the emergency department with acute onset whole-body myoclonic jerks for 1 day. On enquiry, the patient’s parents advised that she had a history of depression over the past 15 years. Intermittently, family ...
Acute disseminated encephalomyelitis (ADEM), first characterized in 1931,1 is a non-specific clinical syndrome of polyfocal central nervous system (CNS) inflammatory demyelination; it is characterized by encephalopathy and large, poorly demarcated cerebral white matter lesions.2,3 Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD), ...
Dr Else Charlotte Sandset, ESO Secretary General and Consultant Neurologist at the Stroke Unit, Department of Neurology, Oslo University Hospital, Norway, provides an overview of some of the high-quality research and scientific advances the stroke community can look forward to at the 8th European Stroke Organisation Conference (ESOC 2022) in Lyon, France and online from 4–6 May 2022.
Ischaemic stroke may occur due to several potential mechanisms. Mechanisms are classically described as large artery atherosclerosis, small-vessel occlusion, cardioembolism, stroke of other determined aetiology (i.e. vasculitis, genetic disorder, etc.) and stroke of undetermined aetiology. Historically, the definition of ...
Studying cerebrospinal fluid (CSF) is essential for diagnosing many central nervous system (CNS) diseases, including infection, inflammation and malignancy. Lumbar puncture is a relatively safe and routinely performed procedure for extracting CSF.1Â In this review, we summarize the essential CSF ...
Cerebral amyloid angiopathy (CAA), also known as congophilic angiopathy, is a recognized cause of lobar intracerebral haemorrhage in patients above the age of 50 years.1Â It is known to be due to deposition of a variant of amyloid (beta-amyloid plaque) in ...
Healthcare workers are currently facing the coronavirus disease 2019 (COVID-19) pandemic and its complications, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients usually suffer from respiratory problems and non-specific neurological symptoms, such as headache, dizziness and ataxia, as well as ...
In the past 4 months, a novel coronavirus originating in Wuhan, China, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has affected more than 200 countries. As of mid-June 2020, there are over 7 million confirmed cases and more than 425,888 deaths worldwide caused by the novel ...
In 2018, two randomised controlled trials, DAWN (the Clinical Mismatch in the Triage of Wake up and Late Presenting Strokes Undergoing Neurointervention with Trevo Thrombectomy Procedure) and DEFUSE 3 (Endovascular Therapy Following Imaging Evaluation for Ischaemic Stroke 3), implemented computed tomography (CT) and ...
Brain metastases (BM) are the most frequent among intracranial brain tumours and their incidence is rising as therapeutic advances are improving the survival of patients with advanced cancer. The incidence of BM has been calculated as 9–17% based on various studies, ...
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