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106 Results Found for “immune profile, ”
Prof. Kenneth Gorson discusses the unmet need in Guillain–Barré syndrome, the phase 3 GBS-02 trial data evaluating tanruprubart, and how complement inhibition could improve recovery while reducing the long-term healthcare burden of this disabling disease. [touchplayvideo video_id="nt33qaui86"] &...
Highlights from the European Academy of Neurology (EAN) 2026 Congress included new phase 3 data in ocular myasthenia gravis, emerging migraine treatments, longer-term results in multiple sclerosis, and advances in deep brain stimulation for Parkinson’s disease. The 12th Congress of the ...
Dr Reisa Sperling discusses the rationale for targeting preclinical Alzheimer's disease, the latest long-term data from the Brainshuttle AD programme evaluating trontinemab, and how the PrevenTRON study could help shift Alzheimer's disease treatment towards prevention. We spoke with Dr Reisa ...
Prof. Lutz Frölich discusses the 48-month Clarity AD open-label extension, including long-term efficacy, clinical meaningfulness, safety and what these findings could mean for patients eligible for lecanemab in Europe. At the European Academy of Neurology (EAN) Congress 2026, Prof. Lutz ...
Prof. Amanda Piquet discusses the KYSA-8 miv-cel trial in refractory stiff-person syndrome, including efficacy findings, safety outcomes and the future role of CD19 CAR T-cell therapy in autoimmune neurologic disease. At the American Academy of Neurology Annual Meeting 2026, Prof. Amanda ...
Leading experts share their perspectives on the most important therapeutic and treatment updates at AAN 2026 and discuss how these findings may shape the future of neurologic care At American Academy of Neurology (AAN) Annual Meeting, Chicago, IL, USA, April 18–22, 2026, major ...
Why this topic matters Autoimmune psychosis (AP) is conceptualized as a psychosis-dominant form of autoimmune encephalitis (AE). In contrast to ‘typical’ AE, in which seizures, impaired consciousness and focal deficits rapidly declare a neurological syndrome, patients with AP can initially ...
Dr Micah Luftig discusses the implications for clinical risk stratification and early intervention, and how EBV-targeted strategies may shape future therapeutic approaches Growing evidence has positioned Epstein–Barr virus (EBV) as a central factor in the development of multiple sclerosis (...
The late-breaking science sessions at AAN Annual Meeting 2026, Chicago, IL, USA brought together a wide range of pivotal and practice-shaping data spanning rare disease, neuroimmunology, headache, epilepsy, neurodegeneration and neuromuscular medicine. Several presentations reported positive phase III findings, while others ...
Prof. Michael Levy highlights the first positive phase 3 trial in MOGAD and what it could mean for future standards of care. Relapse prevention remains one of the greatest unmet needs in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), where recurrent inflammatory ...
The Alzheimer’s and Parkinson’s Diseases Conference (AD/PD) 2026, held in Copenhagen, Denmark, brought together over 5,800 delegates to discuss advances across neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS) and related disorders. ...
We often focus on clinical excellence, but spend less time developing broader skills that could help us better lead with purpose and build more fulfilling, impactful careers. In this episode, part of a mini-series in partnership with LEADderm, Dr Jennifer Soung and Denise Mann explore how clinicians can engage with the media to educate, empower and extend their impact beyond the clinic.
Late-breaking data presented during the LB1: Late-Breaking Research and Clinical Trials session at ACTRIMS Forum 2026, February 5-7, 2026, San Diego, CA, USA, highlighted both progress and persistent challenges across multiple sclerosis (MS) and related neuroimmunological disorders. The session featured studies spanning ...
In this year-end review, we are pleased to share personal highlights from members of the touchNEUROLOGY Editorial Board, whose perspectives offer a window into the innovations that have most influenced clinical practice and research over the past 12 months. Their reflections capture not only the momentum of 2025, but also the promise of what lies ahead as the field continues to evolve.
Between 60% and 80% of cases with dementia worldwide are caused by Alzheimer’s disease (AD), making it the most prevalent type of dementia.1 As of 2025, approximately 60 million people worldwide are affected by dementia, and by 2050, projections suggest a rise to nearly 210 ...
Huntington’s disease (HD) is a fatal, autosomal-dominant, neurodegenerative disorder caused by a cytosine–adenine–guanine (CAG) trinucleotide repeat expansion in the huntingtin (HTT) gene, located on chromosome 4p16.3. When this repeat exceeds 36 units, it leads to the synthesis of ...
In this episode, Nicky speaks with Prof. Georgina Ellison-Hughes from King’s College London about the groundbreaking field of senolytics and their potential to advance the treatment of age-related diseases. From understanding the science behind cellular senescence to how senolytic drugs work and what early clinical trials reveal, this episode explores an exciting frontier in longevity medicine.
Broadest approval to date in generalized myasthenia gravis The FDA approval of nipocalimab for generalized myasthenia gravis (gMG) introduces a targeted therapy within a validated class, offering the potential for durable disease control across the broadest patient population to date. ...
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