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Faculty & Disclosures
Professor Luisa Klotz, MD

Institute of Translational Neurology, University Hospital Münster (UKM), Münster, Germany

Professor Luisa Klotz studied medicine at the University of Bonn (Germany), graduating in 2002. Since 2011, she has been the group leader and head of the clinical trial unit “Neurology and IITs” at the Department of Neurology, University Hospital Münster. She holds a Professorship for “Neurological Immune Therapy,” and her research focuses on immunomodulatory properties of nuclear receptors, pathologic immune responses in multiple sclerosis (MS), and novel therapeutic approaches.

As a clinician scientist, Professor Klotz is particularly interested in the close and continuous integration of basic research and clinical translation. She therefore uses a wide range of methods to answer scientific questions, from animal experiments and studies on human immune cells to conducting her own scientifically oriented clinical studies. Professor Klotz conducts research at the DFG-funded collaborative research center TR128 and 1009, which will be a part of the “Body and Brain Institute Münster” in the future. Professor Klotz is the recipient of several awards, including the Sobek Young Scientist Award for Multiple Sclerosis in 2012 and the renowned DGN Science Award in 2019.

Disclosures: Has received compensation for serving on Scientific Advisory Board for Alexion, Biogen, Bristol-Myers Squibb, Genzyme, Hexal, Horizon, Janssen, Merck Serono, Novartis, Roche, Sandoz, Sanofi, and Viatris. Has received speaker honoraria and travel support from Argenx, Bayer, Biogen, Bristol-Myers Squibb, Genzyme, Grifols, Merck Serono, Novartis, Roche, Santhera, and Teva. Receives research support from the German Research Foundation, the IZKF Münster, Biogen, Immunic AG, Novartis, and Merck Serono.

Professor Patrick Vermersch, MD, PhD

University of Lille, Lille, France

Professor Patrick Vermersch studied medicine at the University Hospital in Lille, France, where he graduated in neurology. He then studied cellular biology from 1990-1994 and received a PhD in biochemical abnormalities associated with Alzheimer’s and other neurodegenerative diseases. This work inspired Professor Vermersch to turn his research interests to MS. In the year 2000, Professor Vermersch and colleagues created the first MS network in northern France, focused on improving MS research and care.

Professor Vermersch currently works in the Lille Neuroscience and Cognition Research Institute at the University of Lille, which focuses on MS and other neuroinflammatory diseases. The department’s principal scientific interests are neuroimmunology and markers of disease evolution.

In 2019, Professor Vermersch became a board member of the European Charcot Foundation. After serving as the vice president of biology and health research at the University of Lille, Professor Vermersch now serves as the director of the graduate school.

His current areas of interest are prognostic markers of MS, the development of new therapeutic targets, and general neuroimmunology. Professor Vermersch participates in many therapeutic protocols on MS as a member of multiple steering committees and has published approximately 480 scientific papers as author or co-author.

Disclosures: Has received speaker honoraria and contributions to attend meetings from Biogen, Sanofi, Novartis, Teva, Merck, Roche, Imcyse,  AB Science, and BMS-Celgene. Has received research support from Novartis, Sanofi, and Roche.

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                touchMEETING HIGHLIGHTS            
            
            
        

    

    




Dissecting Drivers of Disability: A Scientific Exploration of the Central Nervous System Immune Microenvironment in Multiple Sclerosis




 
        


        
    


    
    
             



    

    

                                    

                        

                                                                                                                                                                                                                                                


    
            

            

                                                                                                                

        

        

            

                                                            
Sanofi at EAN 2024

                                                                        
Hear from the experts about our evolving understanding of multiple sclerosis pathophysiology and the role of smoldering neuroinflammation, with a closer look at microglia and Bruton’s Tyrosine Kinase (BTK).


After watching this activity, participants should be better able to:


    

  • Understand drivers of smoldering neuroinflammation
    • 

  • Discuss the role of microglia and BTK
    • 

  • Describe brain penetrance and bioactivity
    • 

  • Outline how to address smoldering neuroinflammation present and future
    • 





For more information, please click below (external site).





                            

        

          
    
                                                                                                                                                                                                                                                                        

                    

                
                


                

                                                                                                                                                                                                                                                                                                


                

                

                                                                                                                                                                                                                                    


     
    

                            
We are pleased to share with you other Sanofi symposium resources on the touchNEUROLOGY platform:


            


                                                            


                

                                            
                            
                        
                                        

                

            
    


        

        
Topics covered in this activity

        
        Multiple Sclerosis        
    


        

            

                
                                            
This activity is sponsored by Sanofi.

                                                                
Sanofi provided financial support and video content, and has had input into the detailed project scope. This activity is provided by Touch Medical Communications (TMC) for touchNEUROLOGY.

                                    
                
                                                                
                                    
            

                            

                    
Unapproved products or unapproved uses of approved products may be discussed; these situations may reflect the approval status in one or more jurisdictions. TMC has advised the sponsor to ensure that they disclose any such references made to unlabelled or unapproved use. No endorsement by TMC of any unapproved products or unapproved uses is either made or implied by mention of these products or uses in TMC activities. TMC accepts no responsibility for errors or omissions.


The views and opinions expressed are those of the faculty and do not necessarily reflect those of any sponsor.


MAT-GLB-2301631-v3-11/2024

Date of preparation: December 2024

                

                    











                

                                            

        
            

    
    

        

            
           

      

        

    


    

        

                    
                
            
            

    
    
 







    






    

        
Topics covered in this activity

        
        Multiple Sclerosis        
    





    



        

    
    

    

    
            
    

 
                                    


       
    
    

            

                
            

        

    





           
            

            

                

                    

                        
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