touchREVIEWS in Neurology is a peer-reviewed, free-to-access, bi-annual, journal that aims to provide insightful and topical articles relevant to the day-to-day practice of busy physicians in the field of neurology.
The journal is of interest to physicians, healthcare professionals and researchers across Europe, US, and ROW, providing practical advice relevant to the clinical setting on diagnosis and treatment within neurology. touchREVIEWS in Neurology endeavours to support these professionals in continuously developing their knowledge, effectiveness and productivity.
Editors-in-Chief: Said R Beydoun and Cris S Constantinescu
Established: January 2006 Frequency: Bi-annual
External Trigeminal Nerve Stimulation as a Non-pharmacological Option for the Prevention and Acute Treatment of Migraine
touchREVIEWS in Neurology. 2022;18(1):Online ahead of journal publication.
Migraine is a common and disabling condition with substantial health and socioeconomic implications. Approximately 1.04 billion people worldwide have migraine disease.1 The condition disproportionately affects women, with 19% of women versus 10% of men reporting a history of migraine.1 Migraine is the second leading cause of years lived with disability across both genders and all ages; further, […]
Dim the Lights: A Narrative Review of Photophobia in Migraine
touchREVIEWS in Neurology 2022;18(1):Online ahead of journal publication
It cannot be seen, cannot be felt, cannot be heard, cannot be smelt. It lies behind stars and under hills, and empty holes it fills. It comes first and follows after, ends life, kills laughter. The Hobbit. JRR Tolkien ‘Darkness’ was the answer to Gollum’s riddle to get out of the tunnel in The Hobbit.1 Darkness is the […]
Neurologic Complications of Immune Checkpoint Inhibitors
touchREVIEWS in Neurology. 2022;18(1): Online ahead of publication
The clinical use of cancer immunotherapy with immune checkpoint inhibitors (ICI) has transformed cancer management and added another effective treatment option for different types of malignancies.1–3 In 2018, the Nobel Prize for medicine and physiology was awarded for the discovery of immune checkpoint molecules. Therapy with ICI has improved patients’ survival and quality of life and […]
A Potential New Alzheimer’s Treatment That May Function by Modulating the Gut Microbiota
touchREVIEWS in Neurology. 2022;18(Suppl. 1): Online ahead of journal publication
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common form of dementia.1 It is characterized by two hallmark pathologies: the deposition of amyloid-β plaques and the neurofibrillary tangles of hyperphosphorylated tau.1 The clinical presentation of AD includes a progressive decline in two or more cognitive domains, which include memory, language, executive and visuospatial function, personality, […]
The Potential Role of Inflammation in Alzheimer’s Disease
touchREVIEWS in Neurology. 2021;18(Suppl. 1): Online ahead of journal publication
Watch the full interview here: Alzheimer’s disease (AD) is the most common form of dementia, and causes a progressive decline in memory, language, executive and visuospatial function, personality and behaviour.1 For many years, there have been only four approved medications to improve cognition in patients with AD, but these only address the symptoms, and do not […]
Molecular Therapy in Myasthenia Gravis
touchREVIEWS in Neurology. 2022;18(1):Online ahead of journal publication
Myasthenia gravis (MG) is an autoimmune disorder caused by autoantibodies against the myoneural junction, which lead to impaired neuromuscular transmission. These antibodies act at the post-synaptic membrane, commonly against the nicotinic acetylcholine receptor (AChR) but in some cases, antibodies to muscle-specific tyrosine kinase (MuSK) or lipoprotein receptor-related protein 4 (LRP4) can be seen. In an […]
GABA-A Receptor Positive Allosteric Modulators as a Novel Approach to Treating Depression: A Review of Available Data
touchREVIEWS in Neurology 2021;17(2):77–84 DOI: https://doi.org/10.17925/USN.2021.17.2.77
Postpartum depression (PPD) is an important mental health problem that is associated with maternal distress and poor maternal–fetal bonding. The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) now classifies PPD as major depressive disorder (MDD), with peripartum onset.1 The distinction ‘with peripartum onset’ is new in DSM-5 and is important, as 50% of ‘postpartum’ major […]
Zolmitriptan for Early Onset of Action in Acute Migraine Attacks
touchREVIEWS in Neurology. 2021;17(2):74–6 DOI: https://doi.org/10.17925/USN.2021.17.2.74
Migraine is a neurologic disease characterized by recurrent attacks of head pain and symptoms such as nausea, photophobia and phonophobia, which last hours to days.1 Attacks themselves can be disabling, and due to the often unpredictable and unavoidable nature of the attacks, the disease itself accounts for substantial disability.2 In fact, migraine affects 12% of the global […]
A Review of Potential Mechanisms of Cryptogenic Stroke and a Recommended Approach to Diagnosis
touchREVIEWS in Neurology. 2021;17(2): 104–9 DOI: https://doi.org/10.17925/USN.2021.17.2.104
Ischaemic stroke may occur due to several potential mechanisms. Mechanisms are classically described as large artery atherosclerosis, small-vessel occlusion, cardioembolism, stroke of other determined aetiology (i.e. vasculitis, genetic disorder, etc.) and stroke of undetermined aetiology. Historically, the definition of stroke of undetermined aetiology has included strokes with multiple potential mechanisms, as well as those with […]
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