The phase 2 study results of ANX005, a humanized monoclonal antibody targeting C1q, for patients with Huntington’s disease were presented at MDS 2022. In this touchNEUROLOGY interview, we speak with Dr Rajeev Kumar (Rocky Mountain Movement Disorders Center, Englewood, CO, USA) to discuss the key results, their significance and the next steps. The abstract entitled […]

ANX005, a humanized monoclonal antibody, is designed to inhibit the classical complement pathway which has been associated with Huntington’s disease (HD). In this touchNEUROLOGY interview, we speak with Dr Rajeev Kumar (Rocky Mountain Movement Disorders Center, Englewood, CO, USA) to discuss the role of complement activation in people living with HD and why ANX005 is […]

Two cases of COVID-19 vaccination associated neurological symptoms were presented, with patients displaying parkinsonism and cognitive dysfunction. In this touchNEUROLOGY interview, we speak with Dr Suman Kushwaha (Institute of Human Behaviour and Allied Sciences (IHBAS), Dilshad Garden, Delhi, India) to discuss the neurological symptoms and investigations leading to the case report conclusions.  The abstract entitled […]

Neurological complications, such as peripheral neuropathy, have been associated with COVID-19 vaccination. In this touchNEUROLOGY interview, we speak with Dr Suman Kushwaha (Institute of Human Behavior and Allied Sciences (IHBAS), Dilshad Garden, Delhi, India) to discuss the neurological symptoms that have been observed.  The abstract entitled ‘Covid vaccine induced parkinsonism and cognitive dysfunction’ was presented […]

This study in patients with Huntington’s disease aimed to assess insulin-like growth factor-1 (IGF-1) levels and hypothalamic function, and the association with non-motor symptoms and brain structure. In this touchNEUROLOGY interview, we speak with Dr Esther Cubo (Hospital Universitario de Burgos, Burgos, Spain) to discuss the study, its findings and future studies that are planned.  […]

The International Parkinson and Movement Disorder Society (MDS) is a professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson’s disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control. touchNEUROLOGY caught up with the MDS President, Prof. Francisco Cardoso, to discuss the upcoming […]

We were delighted to have the opportunity to speak with Indu Subramanian (Geffen School of Medicine, UCLA, and West Los Angeles Veterans Administration, Los Angeles, CA, USA) around the focus of her recently published article entitled: Synergy of pandemics-social isolation is associated with worsened Parkinson severity and quality of life, which was highlighted as a top […]

We were delighted to have the opportunity to speak with Indu Subramanian (Geffen School of Medicine, UCLA, and West Los Angeles Veterans Administration, Los Angeles, CA, USA) around the focus of her recently published article entitled: Synergy of pandemics-social isolation is associated with worsened Parkinson severity and quality of life, which was highlighted as a top […]

Mya C Schiess (McGovern Medical School at UTHealth, Houston, TX, USA) discusses promising findings from a phase I study (ClinicalTrials.gov identifier: NCT02611167), which was the focus of her presentation entitled: Allogeneic bone marrow-derived mesenchymal stem cells safety and tolerability in idiopathic Parkinson’s disease. Questions 1. What is known about the role of inflammation in the […]