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Pavel Burko, Ilias Miltiadis, Mahsa Alavi

Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

High Glucose Levels Associated with Increased Risk for Dementia

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Published Online: Jun 11th 2014

Neurology Today Editor-in-chief Steven P. Ringel, MD, and Associate Editor Robert Holloway, MD, discuss the findings — and offer some caveats: among them, this was an association study and the measures compared are cognitive screening every two years and the average of all glucoses drawn over that time — many variables could be influencing these results. And there is some ambiguity — for example, it’s difficult to discriminate reliably among causes of dementia in this study. Still, the study raises many questions about how neurologists could or should be managing diabetes as a comorbidity, and whether clinicians should be thinking of the brain as another organ with the potential for end organ damage. Read the Sept. 19 Neurology Today story, “High Glucose Levels Associated with Increased Risk for Dementia”:

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