An Introduction to Sleep Disorders
Sleep is essential to human health, but its function, physiology, and pathophysiology have been poorly understood until relatively recently. As well as having negative consequences in social and working life, sleep disturbances and disorders have been associated with neurocognitive disorders, hypertension, dyslipidaemia, cardiovascular disease, weight-related issues, metabolic syndrome, type 2 diabetes, depression and stroke. More than 80 sleep disorders have been identified, some of which very common, including insomnia and obstructive sleep apnoea. Sleep abnormalities are also a common consequence of neurological disorders such as Alzheimer’s disease and Parkinson’s disease. Behavioural treatments have been successful in treating sleeping disorders, while pharmacotherapy is useful for acute insomnia, some parasomnias, narcolepsy and idiopathic hypersomnia.
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Sleep Disorders Content
Pharmacologic Therapy for Narcolepsy
touchREVIEWS in Neurology. 2022;18(1):68–73 DOI: https://doi.org/10.17925/USN.2022.18.1.68
Narcolepsy is a chronic clinical condition primarily characterized by excessive daytime sleepiness (EDS). This may be accompanied by cataplexy, which is a phenomenon of transient muscle weakness triggered by strong emotions, such as laughter, excitement, anger or grief. Narcolepsy is subtyped as type 1 (NT1) if cataplexy is present or type 2 (NT2) if cataplexy […]
Management of excessive daytime sleepiness in patients with obstructive sleep apnea or narcolepsy: A common link for separate conditions
Leading sleep medicine experts explore strategies for the optimal management of excessive daytime sleepiness associated with obstructive sleep apnea or narcolepsy.
- Distinguish EDS from fatigue/tiredness, improving the ability to differentially diagnose OSA and narcolepsy
- Apply non-pharmacological and pharmacological management strategies for EDS in OSA or narcolepsy
- Interpret key efficacy and safety data on emerging therapies for the management of EDS in OSA and narcolepsy
Claudia Trenkwalder, EAN 2021: REM Sleep Behaviour Disorder and Neurodegeneration
touchNEUROLOGY was joined by Prof. Claudia Trenkwalder (Paracelsus-Elena-Hospital, Kassel Germany, University Medical Center, Goettingen, Germany) to discuss her EAN presentation looking into REM Sleep Behaviour Disorder and the connection with neurodegeneration. The abstract entitled: ‘REM Sleep Behaviour Disorder (RBD): future implications for neurodegenerative disease’ was presented at the 7th Congress of the European Academy of […]
Ivana Rosenzweig, Sleep and Breathing 2021: The Link Between Sleep Apnoea and Dementia
We were delighted to speak with Dr Ivana Rosenzweig (Sleep and Brain Plasticity Centre, King’s College London, London, UK) around her talk on the ‘Link between sleep apnoea and dementia: the neuroimaging perspective‘, which was presented at the virtual 2021 Sleep and Breathing Conference, 16-17 April, 2021. Questions What is known about the relationship between […]
Prof. K Ray Chaudhuri: Sleep Issues in Parkinson’s Disease – Diagnosis, Intervention & Practical Advice
In conjunction with the European Parkinson’s Disease Association (EPDA), we had the pleasure of meeting with Prof. K Ray Chaudhuri to discuss sleep issues among people with Parkinson’s Disease. The discussion highlights the appropriate diagnosis of sleep disorders, intervention strategies, practical advice for healthcare professionals, patients and caregivers, and the impact of sleep issues on […]
Rapid Eye Movement Sleep Behaviour Disorder and its Association with Parkinson’s Disease
European Neurological Review. 2019:14(1):16–7. DOI: https://doi.org/10.17925/ENR.2019.14.1.16
Ambra Stefani was born in Italy, where she performed her medical training at the University of Verona. After that she moved to Innsbruck, Austria, where she is currently working as resident and PhD student in the Department of Neurology, Medical University of Innsbruck, Austria. Ambra Stefani has been a member of the sleep research group, […]
Sleep Disorders in Neuromuscular Diseases
US Respiratory & Pulmonary Diseases. 2018;3(1):27–32 DOI: https://doi.org/10.17925/USRPD.2018.3.1.27
Highlights Neuromuscular diseases exhibit a complex array of respiratory physiologic changes that typically progress over time. These physiologic changes can promote significant respiratory abnormalities during sleep, leading to decreased quality of life, significant daytime symptoms, and overall worse survival. There should be a high index of suspicion for the emergence of sleep-related disorders, especially […]
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