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Motor neuron synapses with muscle fiber via electrical impulse transmission and neurotransmitter release, forming neuromuscular junctions , motor neuron, neuroscience
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SOD1-ALS from Gene Discovery to Targeted Therapeutics: A Comprehensive Review

Joshua Newman, Phillipe Corcia, Angela Genge

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

touchREVIEWS in Neurology. 2025;21(1):Online ahead of journal publication

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Wearable Technologies for Parkinson’s Disease: Exploring Their Clinical Potential

Caitríona L Cox, Alistair J Mackett

Parkinson’s disease (PD) is a complex neurodegenerative condition that predominantly affects older people, with a rising prevalence worldwide.1,2 There are many on-going challenges and unmet needs in PD: difficulties in making an accurate diagnosis (particularly in the early stages ...

touchREVIEWS in Neurology. 2024;20(2):13-19
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An Overview of a Stepped-care Approach to Modern Holistic and Subtype-driven Care for Parkinson’s Disease in the Clinic

Karolina Popławska-Domaszewicz, Cristian Falup-Pecurariu, Ray K Chaudhuri

Parkinson’s disease (PD) is characterized by prodromal and clinical stages; the clinical phase is characterized by a constellation of motor and non-motor symptoms (NMS).1 Despite the extensive discussions and publications of the clinical heterogeneity of PD,2 the precise heterogeneous ...

touchREVIEWS in Neurology. 2024;20(1):27-32
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Migraine with Aura Phenomenology and Length

Migraine is a primary headache (HA) disorder affecting about 18 % of women and 6 % of men in the US and Western Europe.1,2 Migraine is essentially a disabling headache, characterized by moderate to severe head pain, usually accompanied by nausea, photophobia, and phonophobia ...

US Neurology, 2014;10(2):111–6 DOI: http://doi.org/10.17925/USN.2014.10.02.111

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