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Motor neuron synapses with muscle fiber via electrical impulse transmission and neurotransmitter release, forming neuromuscular junctions , motor neuron, neuroscience
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

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Emerging data at EAN 2025 reveals key innovations across multiple neurological disease areas.

In this article, you will learn:

  1. Biomarkers are transforming dementia diagnosis with earlier and more accurate detection.
  2. CGRP-targeted therapies are advancing personalized migraine care.
  3. Wearables and digital tools are enhancing movement disorder monitoring.
  4. Data-driven decisions are improving stroke management and outcomes.
  5. Gene and molecular therapies are revolutionizing neuromuscular disease treatment.

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Coverage from: EAN 2025
Simona Sacco

Despite advances in targeted therapies, migraine remains a significant clinical burden.

In this Q&A, you will learn:

  1. How anti-CGRP therapies target migraine-specific pathways to deliver better efficacy and tolerability than traditional treatments.
  2. What real-world data reveal about patient response rates and rare but emerging side effects like Raynaud’s phenomenon.
  3. Why multiple delivery methods, such as oral, subcutaneous, and intravenous, enable higher adherence and more personalized migraine care.

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Prof. Simona Sacco outlines the European Stroke Organisation’s (ESO) strategic priorities to reduce disparities in stroke care across Europe. She discusses the transformative impact of the ESO East programme and the Stroke Action Plan for Europe (SAP-E), and also reflects on the increasing role of artificial intelligence (AI) in stroke diagnostics and treatment pathways.

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Physician burnout is at a critical point. In this episode, Nicky speaks with Dr Alfred Atanda about why so many physicians are burning out and what can be done to change the trend. From personal experience to system-wide solutions, Dr Atanda shares valuable insights on improving physician well-being and building a more effective healthcare culture.

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Launching today, the world’s first multisector advocacy movement dedicated to stroke - the Global Stroke Action Coalition - has issued an urgent call to action to address growing inequities in stroke. Already a leading cause of death and disability, without intervention, the global burden of stroke is projected to rise by a further 50% over the next 25 years, claiming 100 million lives and costing US$1.6 trillion each year.  

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Welcome to this issue of touchREVIEWS in Neurology, where we explore significant advances in neurology, cognitive health, and wearable technology in the management of various chronic conditions. This issue brings together a collection of expert perspectives and research that spans ...

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Article highlights Multiple screening tests are available to screen patients for cognitive impairment, and the Confusion Assessment Method is a helpful test to screen for delirium in the immediate postoperative period. Medicine reconciliation and identification and removal of potentially inappropriate ...

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A study published in The Lancet Neurology reveals a troubling stagnation in the progress against stroke burden worldwide, with incidence rates failing to decline significantly since 2015. This analysis of the Global Burden of Disease (GBD) Study 2021 shows that the absolute numbers of strokes, related deaths and disability-adjusted life years (DALYs) have all risen considerably from 1990 to 2021, despite earlier global efforts aimed at reducing stroke mortality

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Aleš Tomek, Melinda B Roaldsen, Francesca Romana Pezzella

What is the Stroke Action Plan for Europe? Stroke is one of the most enormous burdens to healthcare services.1 Despite our combined efforts, it affects more than one million people annually in Europe. Although we have abundant knowledge regarding stroke ...

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Introduction The term 'stroke' is used to describe an adverse clinical state involving interference of blood circulation to the brain due to obstruction or rupture of blood vessels.1 Stroke was previously categorized into a cardiovascular disorder until the release of ...

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Welcome to our new issue of touchREVIEWS in Neurology, which features a wide range of topical articles covering various areas of neurology. We begin with two practice pearls. The first from Garg et al., focusses on the increasingly important subject ...

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The Stroke Alliance for Europe (SAFE) is a non-profit-making organisation that represents a range of patient groups from across Europe. Their mutual goal is to drive stroke prevention up the European political agenda and prevent the incidence of stroke through ...

Coverage from: AAN Highlights

Ravulizumab has recently been approved by in the US for the treatment of adults with anti-acetylcholine receptor antibody-positive (AChR Ab+) generalized myasthenia gravis (gMG). Prof. James Howard (The University of North Carolina at Chapel Hill, NC, USA) kindly joins touchNEUROLOGY ...

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Coverage from: AAN Highlights

Myasthenia gravis (MG) is a rare autoimmune disorder caused by antibodies that act against the myoneural junction, resulting in weakness of the skeletal muscles. Prof. James Howard (The University of North Carolina at Chapel Hill, CA, USA) discusses the unmet ...

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On behalf of the European Stroke Organisation (ESO) and Stroke Alliance for Europe (SAFE), touchNEUROLOGY are pleased to share the progress made toward reaching the 4 overarching targets of the Stroke Action Plan for Europe (SAP-E). Led by ESO and SAFE, ...

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Ischaemic stroke may occur due to several potential mechanisms. Mechanisms are classically described as large artery atherosclerosis, small-vessel occlusion, cardioembolism, stroke of other determined aetiology (i.e. vasculitis, genetic disorder, etc.) and stroke of undetermined aetiology. Historically, the definition of ...

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Neuropathic pain arises from injury to or disease in the somatosensory nervous system.1 Normal sensation and pain sensation are both impaired and patients may present with peculiar painful characteristics such as allodynia and hyperalgesia.2 Central neuropathic pain includes pain from ...

Coverage from: CONy Highlights

Vida Demarin (International Institute for Brain Health, Zagreb, Croatia) kindly took the time to speak with us on the topic of the debate session she participated in: Should statins be given to people over age 80 for stroke prevention? As co-Chair ...

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