Cortical superficial siderosis (cSS) of the central nervous system is considered a rare condition, observed on gradient echo T2*- weighted magnetic resonance imaging (MRI) as a typical signal hypointensity outlining the brain surface. It is detected as a characteristic ...

Surgery for Occlusive Atherosclerotic DiseaseExtracranial-intracranial (EC-IC) bypass for revascularisation in the setting of atherosclerotic occlusive disease has remained a topic of intense interest and scrutiny over the last four decades. The underlying premise of EC-IC bypass in this setting is ...

Stroke is the second most common cause of death and a major cause of disability worldwide. Because of the ageing population, the burden of stroke is likely to increase during the next 20 years, especially in developing countries.1 The majority (85 %) of ...

Cerebral congophilic or amyloid angiopathy (CAA) is a clinicopathological entity that has been recognised since the early part of the 20th century.1 It is now considered a common cause of primary non-traumatic brain haemorrhage and traditionally it was described in ...

Amyloidoses encompass a heterogeneous group of disorders characterised by the accumulation and extracellular deposition of insoluble aggregates of misfolded fibrillar proteins termed amyloid, which can lead to tissue damage and organ dysfunction.1 They can be exceptionally rare or rather frequent, ...

A tremendous amount of research effort has been put into the understanding and treatment of delayed cerebral vasospasm and its sequelae, namely the development of delayed ischaemic neurological deficits (DIND), since it contributes significantly to overall morbidity and mortality after ...

The treatment of intracranial aneurysms, both ruptured and unruptured, has witnessed a dramatic improvement in outcomes made possible by continuous refinement in microsurgical technique alongside major technological developments and a growing understanding of the physiology of the brain under normal ...

Surgery for Traumatic Brain Injury Surgery for Traumatic Brain Injury The surgical treatment of traumatic lesions in head injury can be challenging and complex, both in terms of indication and technique. Most procedures in neurotrauma are, however, performed by young ...

Primary angiitis of the central nervous system (PACNS) fascinates by the multiplicity of its clinical manifestations, the complexity of its investigation, and the extensiveness of its differential diagnosis (see Table 1). Immunosuppressive therapy is central in the management of PACNS, but ...