An Overview of a Stepped-care Approach to Modern Holistic and Subtype-driven Care for Parkinson’s Disease in the Clinic
Karolina Popławska-Domaszewicz, Cristian Falup-Pecurariu, Ray K Chaudhuri
Parkinson’s disease (PD) is characterized by prodromal and clinical stages; the clinical phase is characterized by a constellation of motor and non-motor symptoms (NMS).1 Despite the extensive discussions and publications of the clinical heterogeneity of PD,2 the precise heterogeneous pathological mechanisms, the natural history of PD and the progression pattern of many NMS remain unclear.3–7 There have also […]