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Joseph Samaha, Jim Dagher, Shayan Abdollah Zadegan

Huntington’s disease (HD) is a neurodegenerative disease inherited in an autosomal dominant manner. It is caused by an expansion of cytosine, adenine, guanine (CAG) repeats within the huntingtin (HTT) gene, which is located on chromosome 4. This pathological expansion of CAG repeats results in the production of a mutant huntingtin protein with an abnormally long polyglutamine […]

Bengt Winblad, EAN 2019 – Ageing and dementia

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Published Online: Jul 9th 2019

We had the great opportunity to chat with our valued European editorial board member Bengt Winblad (Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden) at EAN 2019. We covered aspects of ageing and dementia that were highlighted across various presentations he was involved with at the congress.

Questions

1. What have studies of the dicarboxylate clamp tetratricopeptide motif containing (dcTPR) proteins taught us about Alzheimer’s disease (AD) and other neurodegenerative diseases? (0:04)
2. Could you tell us a little about your recent study on electroencephalography (EEG) in the early detection of synaptic dysfunction in patients with AD? (2:07)
3. What are the implications of these findings for future AD research? (3:15)
4. What are the risks associated with the use of antipsychotic medications in patients with dementia? (4:02)
5. What advice would you give to clinicians considering the use of antipsychotics in their dementia patients? (5:17)

Speaker disclosure: Bengt Winblad has nothing to disclose in relation to this video interview.

Filmed at the 5th Congress of the European Academy of Neurology (EAN), Oslo, Norway, June 2019.

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