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Huntington’s disease (HD) is a neurodegenerative disease inherited in an autosomal dominant manner. It is caused by an expansion of cytosine, adenine, guanine (CAG) repeats within the huntingtin (HTT) gene, which is located on chromosome 4. This pathological expansion of CAG repeats results in the production of a mutant huntingtin protein with an abnormally long polyglutamine […]

Kristen George, AAIC 2022: Experiences of discrimination on cognitive function and ageing among the oldest old: The LifeAfter90 (LA90) Study

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Published Online: Aug 15th 2022

The LifeAfter90 (LA90) Study aims to understand what cognitive ageing and dementia look like among individuals aged 90 and above. In this interview, Dr Kristen George (University of California Davis School of Medicine, University of California, Davis, CA, USA) discussed what the study found in terms of the effect of discrimination on the cognitive function of this population.  

The poster entitled ‘Experiences of Discrimination on Cognitive Function and Aging among the Oldest Old: LifeAfter90 (LA90) Study’ was presented at the annual Alzheimer’s Association International Conference (AAIC), 31 July – 4 August 2022. 

Questions:

1. Could you give us a brief overview of the LifeAfter90 study and its aims? (00:28)

2. What is known about the impact of discrimination on the cognitive function in older adults? (01:29)

3. What were the findings of the LA90 study in terms of the experiences of discrimination on cognitive function and ageing? (02:13)

4. What can be done to reduce discrimination to support cognitive function in older populations? (04:04)

5. What questions remain unanswered and what future studies are planned? (05:02)

Disclosures: Kristen George receives grant/research support from the National Institutes of Health.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Marianna Mignani.

Filmed as a highlight of AAIC 2022

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