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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

Yona Levites, AD/PD 2021: Immunotherapeutic approaches in Alzheimer’s Disease (Part 2)

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Published Online: Mar 17th 2021

We had the pleasure of meeting with Yona Levites (Center for Translational Research in Neurodegenerative Disease, University of Florida, Gainesville, FL, USA ) to discuss her phase 1 study investigating the scFv-CD protein as a framework for identifying an optimized immunotherapy for Alzheimer’s Disease, and potentially other neurodegenerative disorders.

Part 1 of the discussion can be viewed here.

The abstract entitled ‘Immunotherapeutic approaches in Alzheimer’s Disease’ was presented at The 15th International Conference for Alzheimer’s & Parkinson’s Diseases (Virtual), March 8-14, 2021.

Questions:

  1. Could you give us a brief description of the scFv-CD protein you have developed? (0:20)
  2. What have you learned from preclinical studies of the scFv-CD protein? (2:06)

Disclosures: Yona Levites has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media.

Filmed as a highlight of AD/PD Virtual 2021.

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