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Joseph Samaha, Jim Dagher, Shayan Abdollah Zadegan

Huntington’s disease (HD) is a neurodegenerative disease inherited in an autosomal dominant manner. It is caused by an expansion of cytosine, adenine, guanine (CAG) repeats within the huntingtin (HTT) gene, which is located on chromosome 4. This pathological expansion of CAG repeats results in the production of a mutant huntingtin protein with an abnormally long polyglutamine […]

Brain Injury Biomarker Research

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Published Online: Mar 15th 2015

Traumatic brain injury (TBI) is the leading cause of death and disability among young adults. While improvements in safety and emergency response times have increased TBI survival, this has heightened the need for reliable methods to identify patients at risk of developing secondary pathologies. Biomarkers have proven useful for the diagnosis of many pathological conditions including cancer, heart failure, infection, and genetic disorders.

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