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A digital rendering of a human brain with highlighted neural pathways and electric activity, visualizing brain function.
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Pavel Burko, Ilias Miltiadis, Mahsa Alavi

Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

Brain Injury Biomarker Research

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Published Online: Mar 15th 2015

Traumatic brain injury (TBI) is the leading cause of death and disability among young adults. While improvements in safety and emergency response times have increased TBI survival, this has heightened the need for reliable methods to identify patients at risk of developing secondary pathologies. Biomarkers have proven useful for the diagnosis of many pathological conditions including cancer, heart failure, infection, and genetic disorders.

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