Treatment guidelines recommend preventive therapy for migraine, based primarily on the frequency of migraine attacks.1Â Migraine-related burden of disease increases with the number of headache days; however, even fewer than 4 headache days per month can result in severe disability in addition to impairment during individual episodes.2,3Â The needs of patients with migraine go beyond simply reducing […]
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In this narrative review, we aim to introduce the reader to the history of calcitonin gene-related peptide (CGRP) discovery and its involvement in migraine pathophysiology. We will then look at drug development and clinical trials in migraine. We will additionally discuss other headache disorders where CGRP may play a role and, last, we will discuss areas of further study. […]
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touchREVIEWS in Neurology is a peer-reviewed, free-to-access, bi-annual neurology journal comprising review articles, case reports, practice guides, theoretical discussions, and original research. It features balanced and comprehensive articles written by leading authorities, addressing the most important and salient developments in the field of neurology.
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