Phenomenology and clinical significance of OFF episodes in Parkinson’s disease Werner Poewe Department of Neurology, Innsbruck Medical University, Innsbruck, Austria The emergence of OFF episodes in Parkinson’s disease (PD) marks the transition from the so-called ‘honeymoon’ period of good disease control to a phase in which motor fluctuations start to occur, approximately 3–5 years after […]
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Parkinson’s disease (PD) is a complex neurodegenerative condition that predominantly affects older people, with a rising prevalence worldwide.1,2 There are many on-going challenges and unmet needs in PD: difficulties in making an accurate diagnosis (particularly in the early stages of the disease), troubling side effects associated with the available pharmacological treatments, a lack of effective disease-modifying therapies […]
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touchREVIEWS in Neurology is a peer-reviewed, free-to-access, bi-annual neurology journal comprising review articles, case reports, practice guides, theoretical discussions, and original research. It features balanced and comprehensive articles written by leading authorities, addressing the most important and salient developments in the field of neurology.
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