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Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

ECTRIMS 2017 – Jeffrey Cohen Interview

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Published Online: Nov 3rd 2017

Jeffrey Cohen talks to us about proposed new updates to the McDonald criteria for MS diagnosis.

 

1. Why are revisions to the McDonald criteria needed? (0:05)
2. What are the limitations of the current criteria in special populations (i.e. paediatric, Asian and Latin American people)? (0:38)
3. What revisions have been proposed to the definition of MS phenotypes? (1:11)
4. How have the revisions reflected the increased value of CSF in diagnosis of MS? (2:23)
5. What revisions have been made to the MRI criteria for the diagnosis of MS? (3:46)

Speaker disclosures: Jeffrey Cohen serves as a consultant to Adamas and Celgene, and as Co-Editor of Multiple Sclerosis Journal – Experimental, Translational and Clinical.

 

Filmed at the 7th Joint ECTRIMS-ACTRIMS Meeting, Paris, France, October 2017.

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