Trending Topic

Motor neuron synapses with muscle fiber via electrical impulse transmission and neurotransmitter release, forming neuromuscular junctions , motor neuron, neuroscience
15 mins

Trending Topic

Developed by Touch
Mark CompleteCompleted
BookmarkBookmarked

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

Joachim Burman, EAN 2019 – Non-myeloablative hematopoietic stem cell transplant in MS: MIST trial

Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied
Published Online: Jul 8th 2019

Joachim Burman (Uppsala University, Sweden) explains to us the rationale for the use of autologous non-myeloablative hematopoietic stem cell transplant (autoHSCT) in patients with relapsing remitting multiple sclerosis, and shares his insight on the MIST (Multiple Sclerosis International Stem cell Transplant) study findings.

Questions
1. What is the rationale for the use of autologous non-myeloablative hematopoietic stem cell transplant (autoHSCT) in patients with relapsing remitting multiple sclerosis? (0:04)
2. Could you tell us a little about the MIST (Multiple Sclerosis International Stem cell Transplant) study and its findings? (0:40)
3. What are the risks of this treatment? (1:44)
4. Which patients are most likely to respond to autoHSCT? (2:43)
5. What were the limitations of the MIST study and what further studies are planned? (3:11)

Speaker disclosure: Joachim Burman has nothing to disclose in relation to this video interview.

Filmed at the 5th Congress of the European Academy of Neurology (EAN), Oslo, Norway, June 2019.

Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied
Close Popup