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Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

Kerstin Hellwig: Multiple Sclerosis Treatment during Pregnancy and Breastfeeding

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Published Online: Mar 7th 2022
For women who have received an multiple sclerosis (MS) diagnosis and are pregnant, the risk for relapse during and after pregnancy varies. Prof. Kerstin Hellwig discusses the current recommendations regarding MS treatment during pregnancy, recent research investigating the discontinuation of therapy before and during pregnancy, and she also discusses the safety of MS therapies during breastfeeding.

Questions:

  1. What is the effect of pregnancy and the postpartum period on relapses in women with MS?
  2. What are the current recommendations regarding MS treatment during pregnancy?
  3. What has recent research discovered about the impact of discontinuing MS therapies before or during pregnancy?
  4. What is known about the safety of MS therapies during breastfeeding?

Disclosures: Kerstin Hellwig has received grant/research support from Biogen, Teva, Genzyme, Novartis and Roche; has is on an advisory board Biogen, Teva, Genzyme, Novartis and Roche; and a speakers bureau participant for Biogen, Teva, Genzyme, Novartis and Roche.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

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