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Motor neuron synapses with muscle fiber via electrical impulse transmission and neurotransmitter release, forming neuromuscular junctions , motor neuron, neuroscience
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

Topographical Model of MS Offers More Holistic View of Disease

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Published Online: Sep 8th 2015

Stephen Krieger, MD, of Mount Sinai in New York City, a protege of Fred Lublin, MD, the creator of the three-category MS model, explains how the new topographical model of MS, presented at the American Academy of Neurology 2015 meeting, builds upon existing concepts of the disease.

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