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Motor neuron synapses with muscle fiber via electrical impulse transmission and neurotransmitter release, forming neuromuscular junctions , motor neuron, neuroscience
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

Alzheimer's Disease and Dementia

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An Introduction to Alzheimer's Disease and Dementia

Major advances in the understanding of the pathogenesis of Alzheimer’s disease (AD), the most common form of dementia, have occurred over recent years, but the need for truly disease-modifying therapies remains. Novel pharmacotherapy strategies under investigation include the repurposing of medications used to treat non-AD illnesses and multi-target-directed ligands, offering promise in this challenging treatment landscape.

Browse video highlights and short articles from the conference hub, providing insights into the latest updates from major conferences and peer-reviewed articles from our journal touchREVIEWS in Neurology. This is complimented by a range of educational activities developed in collaboration with our leading expert faculty.

Our supporting partners do not constitute an endorsement of the content on this page.

touchVisionary Voices
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Physician burnout is at a critical point. In this episode, Nicky speaks with Dr Alfred Atanda about why so many physicians are burning out and what can be done to change the trend. From personal experience to system-wide solutions, Dr Atanda shares valuable insights on improving physician well-being and building a more effective healthcare culture.

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What if your medical degree could launch more than a clinical career? In this candid and compelling read, Dr Jon Edelson shares his lessons for early-career clinicians ready to think beyond the bedside and explore the business of medicine.

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In this episode of Visionary Voices, Dr Anthony Caggiano, Chief Medical Officer at Cognition Therapeutics, joins us to explore how biomarkers are transforming our understanding of Alzheimer’s disease, from diagnosis and disease progression to drug development and the future of clinical care.

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The Lumipulse G pTau217/ß-Amyloid 1-42 Plasma Ratio test, the first diagnostic blood test designed to aid in the evaluation of Alzheimer’s disease (AD), has been cleared by the US Food and Drug Administration (FDA). The Lumipulse G pTau217/ß...

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In this episode, we explore the future of continuing medical education (CME) with the team behind touchIME. Hannah Fisher and Matthew Goodwin share insights into global and US trends, the importance of patient inclusivity and how educational outcomes are evolving to better measure the direct impact of learning on clinical practice and patient care.

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In this Q&A, Dr Andy Liu, Associate Professor of Neurology at Duke University School of Medicine, discusses his presentation on the clinical use of lecanemab in Alzheimer’s disease. Drawing on real-world experience and findings from the 2022 CLARITY AD study, Dr Liu explores the treatment’s benefits, challenges in daily practice and the importance of patient-centred care in this evolving therapeutic landscape.

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The 2025 Annual Meeting of the American Academy of Neurology in San Diego brought together over 14,500 neurology professionals from 110 countries and all 50 US states, alongside more than 300 exhibiting companies. It was a week filled with inspiring science, learning, and global collaboration—all in support of advancing brain health for all. Among the many highlights were the late-breaking abstracts, showcasing some of the most exciting developments in neurology. From this impressive selection, we’ve chosen five standout presentations that reflect the innovation and momentum seen throughout the meeting.

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In this Q&A, Dianne Gove, PhD, Director for Public Involvement and Ethics at Alzheimer Europe discusses the impact of stigma on the quality of life of people living with dementia, explores strategies for raising awareness and challenging misconceptions, and highlights the role of healthcare professionals and Alzheimer Europe’s key initiatives in combating stigma, including plans for 2025.

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As 2024 draws to a close, we’re celebrating a fantastic year of content.

touchVisionary Voices
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In this episode, we’re joined by Bradley Love, Professor of Cognitive and Decision Sciences at UCL, ELLIS fellow, and creator of BrainGPT. We discuss how this large language model is poised to assist researchers in advancing their work.

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Welcome to this issue of touchREVIEWS in Neurology, where we explore significant advances in neurology, cognitive health, and wearable technology in the management of various chronic conditions. This issue brings together a collection of expert perspectives and research that spans ...

33 mins
CE/CME accredited
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touchPANEL DISCUSSION
Prof. Jeffrey Cummings, Prof. Krista Lanctôt, Prof. James Galvin

Three experts consider agitation in Alzheimer’s dementia with a focus on pharmacological treatment options.

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Cognitive impairment is the hallmark symptom of Alzheimer’s disease (AD); however, neuropsychiatric symptoms (NPS), including psychosis, agitation and mood disturbances, are common not only in AD but also in Parkinson’s disease, dementia with Lewy bodies, frontotemporal dementia and ...

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A new study published in Nature Neuroscience1 has uncovered significant insights into the progression of Alzheimer’s disease (AD), providing a new understanding of how the disease damages the brain. Funded by the National Institutes of Health (NIH) and led by researchers from the Allen Institute, this study used advanced brain mapping and genetic tools to explore the cellular-level changes that occur throughout AD. The findings reveal that Alzheimer's progresses in two distinct phases, offering potential avenues for early diagnosis and treatment strategies.

29 mins
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Watch leading experts explain the shifting diagnostic paradigm in Alzheimer’s disease using case studies demonstrating the utility of biomarkers

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In this next Q&A we welcome Prof. Dr Murat Emre. Prof. Emre studied medicine in Istanbul University and specialized in neurology in Zurich University Hospital in Zurich, Switzerland. After his training he did fellowships in movement disorders in Queen Square Hospital London and in behavioural neurology in Beth Israel Hospital, Harvard Medical School in Boston, he also worked in clinical research to develop new drugs for Parkinson's disease and Azlheimer disease. Upon his return to Turkey he founded the Movement Disorders and behavioural Neurology Unit in the Department of Neurology, İstanbul Faculty of Medicine. His main areas of interest are Parkinson!'s disease, in particular cognitive aspects/dementia and Alzheimer disease.

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In our next expert Q&A we are delighted to welcome Prof. Bengt Winblad. Prof. Winblad is a prominent figure in geriatric medicine and Alzheimer's research, having served as Head of the Division of Neurogeriatrics at Karolinska Institutet and ...

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