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Pavel Burko, Ilias Miltiadis, Mahsa Alavi

Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

Parkinson’s Disease: Progress and Promise in Stem Cell Research

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Published Online: Nov 7th 2012

Parkinson’s disease is a neurodegenerative disease that affects nearly a million people in the United States. The symptoms include tremors, slow movement, muscle rigidity and less facial expression. No cure exists for the disease and current medications become less effective over time. William Langston, CEO and scientific director of the Parkinson’s Institute, discusses stem cell-based research strategies to better understand the disease and to find new therapies. The Parkinson’s Institute has an Early Translation grant from CIRM.

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