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Motor neuron synapses with muscle fiber via electrical impulse transmission and neurotransmitter release, forming neuromuscular junctions , motor neuron, neuroscience
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

Multi-modal MRI-Diagnostic Biomarker:Amyotrophic Lateral Sclerosis

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Published Online: May 5th 2014

The University of Michigan’s Bradley R. Foerster, M.D., Ph.D., discusses a technique that uses two different types of magnetic resonance imaging (MRI) on the brain to more accurately diagnose amyotrophic lateral sclerosis (ALS) than using a single type of MRI alone. Dr. Foerster, an Emerging Scholar at the A. Alfred Taubman Medical Research Institute, says the finding that could lead to earlier diagnoses of the deadly disease and ultimately to more effective treatments for patients. The findings were published in the ‘Annals of Clinical and Translational Neurology.’

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