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Isabella Henderson, Nisali A Gunawardane, Ruben I Kuzniecky

Epilepsy affects approximately 1% of the global population, with one-third of patients remaining refractory to medical therapy.1 Drug-resistant epilepsy (DRE), defined as the failure of two appropriately chosen antiseizure medications (ASMs) to achieve seizure freedom, poses significant risks, including injury and sudden unexpected death in epilepsy (SUDEP).2 Early identification of DRE is critical to enable timely exploration […]

Brain Injury Biomarker Research

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Published Online: Mar 15th 2015

Traumatic brain injury (TBI) is the leading cause of death and disability among young adults. While improvements in safety and emergency response times have increased TBI survival, this has heightened the need for reliable methods to identify patients at risk of developing secondary pathologies. Biomarkers have proven useful for the diagnosis of many pathological conditions including cancer, heart failure, infection, and genetic disorders.

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