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Pavel Burko, Ilias Miltiadis, Mahsa Alavi

Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

Henry Ma, ESOC 2019 – Meta-analysis of EXTEND, ECASS4-EXTEND and EPITHET trials

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Published Online: Jun 12th 2019

Henry Ma, on behalf of the EXTEND (Extending the Time for Thrombolysis in Emergency Neurological Deficits [International], NCT01580839), ECASS4-EXTEND (European Cooperative Acute Stroke Study-4: Extending the time for thrombolysis in emergency neurological deficits, ISRCTN71616222) and EPITHET (Echoplanar Imaging Thrombolysis Evaluation Trial, NCT00238537) Investigators, discusses important results presented at ESOC 2019 from a meta-analysis of individual patient data from these trials.

Content produced in Milan, Italy and shared with kind authorisation of the European Stroke Organisation (ESO) and the European Stroke Organisation Conference (ESOC 2019). 

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