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Joseph Samaha, Jim Dagher, Shayan Abdollah Zadegan

Huntington’s disease (HD) is a neurodegenerative disease inherited in an autosomal dominant manner. It is caused by an expansion of cytosine, adenine, guanine (CAG) repeats within the huntingtin (HTT) gene, which is located on chromosome 4. This pathological expansion of CAG repeats results in the production of a mutant huntingtin protein with an abnormally long polyglutamine […]

Claudia Trenkwalder, EAN 2021: REM Sleep Behaviour Disorder and Neurodegeneration

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Published Online: Jul 5th 2021

touchNEUROLOGY was joined by Prof. Claudia Trenkwalder (Paracelsus-Elena-Hospital, Kassel Germany, University Medical Center, Goettingen, Germany) to discuss her EAN presentation looking into REM Sleep Behaviour Disorder and the connection with neurodegeneration.

The abstract entitled: ‘REM Sleep Behaviour Disorder (RBD): future implications for neurodegenerative disease’ was presented at the 7th Congress of the European Academy of Neurology – Virtual 2021.

Questions:

  1. What are the diagnostic criteria for REM Sleep Behaviour Disorder (RBD)? (0:30)
  2. What are the clinical implications of RBD? (2:42)
  3. What are the connections between RBD and neurodegeneration? (4:45)
  4. What are the advances in preventative, slowing or curative α-synucleinopathy treatments? (6:07)

Disclosures: Claudia Trenkwalder has received honorarium from UCB for educational lectures and consulting.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

Filmed as a highlight of the EAN Congress, Virtual 2021

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