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Isabella Henderson, Nisali A Gunawardane, Ruben I Kuzniecky

Epilepsy affects approximately 1% of the global population, with one-third of patients remaining refractory to medical therapy.1 Drug-resistant epilepsy (DRE), defined as the failure of two appropriately chosen antiseizure medications (ASMs) to achieve seizure freedom, poses significant risks, including injury and sudden unexpected death in epilepsy (SUDEP).2 Early identification of DRE is critical to enable timely exploration […]

Claudia Trenkwalder, EAN 2021: REM Sleep Behaviour Disorder and Neurodegeneration

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Published Online: Jul 5th 2021

touchNEUROLOGY was joined by Prof. Claudia Trenkwalder (Paracelsus-Elena-Hospital, Kassel Germany, University Medical Center, Goettingen, Germany) to discuss her EAN presentation looking into REM Sleep Behaviour Disorder and the connection with neurodegeneration.

The abstract entitled: ‘REM Sleep Behaviour Disorder (RBD): future implications for neurodegenerative disease’ was presented at the 7th Congress of the European Academy of Neurology – Virtual 2021.

Questions:

  1. What are the diagnostic criteria for REM Sleep Behaviour Disorder (RBD)? (0:30)
  2. What are the clinical implications of RBD? (2:42)
  3. What are the connections between RBD and neurodegeneration? (4:45)
  4. What are the advances in preventative, slowing or curative α-synucleinopathy treatments? (6:07)

Disclosures: Claudia Trenkwalder has received honorarium from UCB for educational lectures and consulting.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

Filmed as a highlight of the EAN Congress, Virtual 2021

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