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Isabella Henderson, Nisali A Gunawardane, Ruben I Kuzniecky

Epilepsy affects approximately 1% of the global population, with one-third of patients remaining refractory to medical therapy.1 Drug-resistant epilepsy (DRE), defined as the failure of two appropriately chosen antiseizure medications (ASMs) to achieve seizure freedom, poses significant risks, including injury and sudden unexpected death in epilepsy (SUDEP).2 Early identification of DRE is critical to enable timely exploration […]

Chia-Chun Chiang, AAN 2021: Real World Efficacy, Tolerability and Safety of Ubrogepant

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Published Online: May 10th 2021

We had the pleasure of meeting with Chia-Chun Chiang (Mayo Clinic, Rochester, MN, USA) to discuss a real world study of ubrogepant in participants with acute migraine.

The abstract entitled: ‘Real World Efficacy, Tolerability and Safety of Ubrogepant’ was presented at the American Academy of Neurology Virtual Annual Meeting 2021.

Questions:

  1. What is the current role of gepants in the treatment armamentarium for migraine? (0:30)
  2. What have clinical studies taught us about the efficacy and safety of ubrogepant? (1:57)
  3. Could you tell us a little about your real world study and its findings? (3:33)
  4. What factors were found to predict a good response to ubrogepant? (5:35)

Disclosures: Chia-Chun Chiang has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

Filmed as a highlight of AAN Annual Virtual Meeting 2021.

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