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Huntington’s disease (HD) is a neurodegenerative disease inherited in an autosomal dominant manner. It is caused by an expansion of cytosine, adenine, guanine (CAG) repeats within the huntingtin (HTT) gene, which is located on chromosome 4. This pathological expansion of CAG repeats results in the production of a mutant huntingtin protein with an abnormally long polyglutamine […]

Serena Orr, AHS 2021: Stress and Peak Pain Severity in Chronic Migraine

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Published Online: Jul 5th 2021

We had the great pleasure of meeting with Dr. Serena Orr (Hotchkiss Brain Institute, University of Calgary, Calgary, Canada) to discuss the relationship between peak pain severity in chronic migraine, and its relationship to stress.

The abstract ‘The Relationship Between Perceived Stress and Peak Pain Severity in Individuals with Chronic Migraine: A Longitudinal Cohort Study Using Daily Prospective Diary Data’ was presented at the American Headache Society (AHS) Virtual Annual Scientific Meeting 2021, 3-6 June 2021

Questions:

  1. What is known about the relationship between perceived stress and migraine?
  2. What were the objectives and design of your study?
  3. Could you tell us a little about the N1-Headacheâ„¢ digital health platform, and the methodology for assessing perceived stress?
  4. What were the study findings?
  5. What factors might explain the variability among individuals in the relationship between same day peak migraine severity and perceived stress?

Disclosures: Dr. Serena Orr has research funding from the Alberta Children’s Hospital Research Institute and the Canadian Institutes of Health Research, and receives royalties for book publications from Cambridge University Press.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

Filmed as a highlight of AHS Virtual Annual Scientific Meeting 2021

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