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Joseph Samaha, Jim Dagher, Shayan Abdollah Zadegan

Huntington’s disease (HD) is a neurodegenerative disease inherited in an autosomal dominant manner. It is caused by an expansion of cytosine, adenine, guanine (CAG) repeats within the huntingtin (HTT) gene, which is located on chromosome 4. This pathological expansion of CAG repeats results in the production of a mutant huntingtin protein with an abnormally long polyglutamine […]

Chia-Chun Chiang, AAN 2021: Real World Efficacy, Tolerability and Safety of Ubrogepant

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Published Online: May 10th 2021

We had the pleasure of meeting with Chia-Chun Chiang (Mayo Clinic, Rochester, MN, USA) to discuss a real world study of ubrogepant in participants with acute migraine.

The abstract entitled: ‘Real World Efficacy, Tolerability and Safety of Ubrogepant’ was presented at the American Academy of Neurology Virtual Annual Meeting 2021.

Questions:

  1. What is the current role of gepants in the treatment armamentarium for migraine? (0:30)
  2. What have clinical studies taught us about the efficacy and safety of ubrogepant? (1:57)
  3. Could you tell us a little about your real world study and its findings? (3:33)
  4. What factors were found to predict a good response to ubrogepant? (5:35)

Disclosures: Chia-Chun Chiang has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

Filmed as a highlight of AAN Annual Virtual Meeting 2021.

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