Overview of topics covered in this review Glutamate and the basal ganglia in the healthy brain Glutamate and glutamate receptors – role in motor circuitry The basal ganglia – anatomy and function The basal ganglia pathways and the role of glutamate in the healthy brain Glutamate and the basal ganglia in the parkinsonian brain Glutamate […]
Parkinson’s disease (PD) is a complex neurodegenerative condition that predominantly affects older people, with a rising prevalence worldwide.1,2 There are many on-going challenges and unmet needs in PD: difficulties in making an accurate diagnosis (particularly in the early stages of the disease), troubling side effects associated with the available pharmacological treatments, a lack of effective disease-modifying therapies […]
European Neurological Review is a peer-reviewed, free-to-access, bi-annual neurology journal comprising review articles, case reports, practice guides, theoretical discussions, and original research. It features balanced and comprehensive articles written by leading authorities, addressing the most important and salient developments in the field of neurology in practical terms.