Introduction Presented by: Richard B Lipton Albert Einstein College of Medicine, Bronx, NY, US Current guidelines recommend preventive treatments for people who experience frequent and disabling migraine headaches, specifically those suffering headaches on 4 or more days/month.1 However, only one-third of people eligible for preventive treatments actually receive them, and of these, over three-quarters discontinue […]

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In this narrative review, we aim to introduce the reader to the history of calcitonin gene-related peptide (CGRP) discovery and its involvement in migraine pathophysiology. We will then look at drug development and clinical trials in migraine. We will additionally discuss other headache disorders where CGRP may play a role and, last, we will discuss areas of further study. […]
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