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Joseph Samaha, Jim Dagher, Shayan Abdollah Zadegan

Huntington’s disease (HD) is a neurodegenerative disease inherited in an autosomal dominant manner. It is caused by an expansion of cytosine, adenine, guanine (CAG) repeats within the huntingtin (HTT) gene, which is located on chromosome 4. This pathological expansion of CAG repeats results in the production of a mutant huntingtin protein with an abnormally long polyglutamine […]

Heinz Reichmann, EAN 2020 – OPTIPARK Study in Patients with Parkinson’s and Motor Fluctuations

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Published Online: May 23rd 2020

Heinz Reichmann (Universitätsklinikum Carl Gustav Carus, Dresden, Germany) shares key findings and expert insights into the OPTIPARK study, a prospective, open-label, uncontrolled, single-group, multi-centre trial in patients with Parkinson’s disease and wearing-off motor fluctuations (ClinicalTrials.gov Identifier: NCT02847442).

Questions
1. What were the aims and design of the OPTIPARK study? (
0:05)
2. What were the efficacy and safety findings of the study? (
2:24)
3. What were the major strengths and weaknesses of this study? (
4:49)

Also see linked video: Heinz Reichmann, EAN 2020 – Unmet Needs in the Treatment of Parkinson’s

Speaker disclosure: Heinz Reichmann reports having received honoraria from Bial for his participation in advisory board meetings and satellite symposia.

Support: Interview and filming supported by Touch Medical Media.

Filmed at the 6th Congress of the European Academy of Neurology (EAN) and 1st EAN Virtual Congress, May 2020.

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