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Motor neuron synapses with muscle fiber via electrical impulse transmission and neurotransmitter release, forming neuromuscular junctions , motor neuron, neuroscience
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

Diaphragm Pacing for ALS Patients

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Published Online: Apr 9th 2014

In a study presented at the AAN annual 2013 meeting last March, researchers reported that three preoperative tests combined with clinical judgment are helpful in predicting diaphragm excitability in amyotrophic lateral sclerosis (ALS) patients. In a video interview, Neurology Today’s Editor-in-Chief Steven P. Ringel, MD, and Associate Editor Robert Holloway, MD, discuss the implications of these findings for ALS experts and patients.

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