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Pavel Burko, Ilias Miltiadis, Mahsa Alavi

Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

Multi-modal MRI-Diagnostic Biomarker:Amyotrophic Lateral Sclerosis

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Published Online: May 5th 2014

The University of Michigan’s Bradley R. Foerster, M.D., Ph.D., discusses a technique that uses two different types of magnetic resonance imaging (MRI) on the brain to more accurately diagnose amyotrophic lateral sclerosis (ALS) than using a single type of MRI alone. Dr. Foerster, an Emerging Scholar at the A. Alfred Taubman Medical Research Institute, says the finding that could lead to earlier diagnoses of the deadly disease and ultimately to more effective treatments for patients. The findings were published in the ‘Annals of Clinical and Translational Neurology.’

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