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Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

Said Beydoun, AAN 2019 – Current and emerging therapies for myasthenia gravis (Part 1)

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Published Online: May 29th 2019

US Neurology Editor-in-Chief, Said Beydoun (Keck Medical Center of USC, University of Southern California, CA, USA), discusses challenges in the diagnosis of myasthenia gravis and limitations of existing therapies.

Questions

  1. What are the major challenges in the diagnosis of myasthenia gravis? (0:04)
  2. What are the limitations of glucocorticoids and other immunosuppressive therapies in the treatment of myasthenia gravis? (1:58)

View Part 2 of this expert interview here.

Speaker disclosures: Said Beydoun has received research grants from Argenx, Catalyst and UCB, and is a consultant, advisory board member and speaker for Alexion.

Filmed at the American Academy of Neurology (AAN) Annual Meeting, Philadelphia, USA, May 2019.

 

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