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Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

José A. López García, EAN 2021: Clinical Development of SAN711, and its Potential to Treat Neuropathic Pain

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Published Online: Aug 9th 2021

It was a pleasure to meet with José A. López García (University of Alcalá, Alcalá de Henares, Spain) to discuss the clinical development of SAN711, a selective GABAA α3 receptor positive allosteric modulator for the potential treatment of neuropathic pain.

The abstract entitled: ‘SAN711 a selective GABAA α3 receptor positive allosteric modulator as a novel treatment for trigeminal neuralgia ’ was presented at the 7th Congress of the European Academy of Neurology – Virtual 2021.

Questions:

  1. Could you tell us a little about SAN711, its selectivity and mechanism of action? (0:16)
  2. What are the objectives and design of the Phase 1 study of SAN711? (8:53)
  3. What are the intended clinical indications of SAN711? (10:55)

Disclosures: José A. López García has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch

Filmed as a highlight of the EAN Congress, Virtual 2021

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