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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

Daniel van Wamelen, AAN 2019 – Targeting non-motor symptoms in Parkinson’s disease (Part 2)

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Published Online: May 22nd 2019

Daniel van Wamelen (The Maurice Wohl Clinical Neuroscience Institute, King’s College London, UK) discusses non-motor symptoms in Parkinson’s disease (PD) and the repurposing of existing medication in PD to target new areas such as cognition.

 

Questions

  1. Are objective measures available for non-motor symptoms of Parkinson’s disease (PD), similar to objective measures for motor symptoms? (0:04)
  2. How can existing drugs for PD be repurposed to target non-motor symptoms in PD? (2:06)
  3. What is the effect of advanced therapies, such as apomorphine and intrajejunal levodopa infusion, on non-motor symptoms in PD? (4:29)

 

View Part 1 of this expert interview here.

 

Speaker disclosure: Daniel van Wamelen has nothing to disclose in relation to this video interview.

 

Filmed at the American Academy of Neurology (AAN) Annual Meeting, Philadelphia, USA, May 2019.

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