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Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare, autoimmune neurological disorder in which peripheral nerve demyelination typically results in weakness, impaired limb sensation, fatigue and pain.1–4 CIDP may adversely affect activities of daily living, with a substantial impact on functional ability and psychological well-being.2–6 Primary treatment goals are reducing symptoms, improving functional status and maintaining long-term remission.7 The […]

Heinz Reichmann, MDS 2020 – Gut Microbiome and Parkinson’s Disease

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Published Online: Sep 23rd 2020

As always, we were pleased to have the opportunity to catch-up with valued editorial board member Heinz Reichmann (Technische Universität Dresden, Dresden, Germany), who spoke to us on the topic of the lecture he gave during the on-demand sessions entitled: The Gut Microbiome in the Pathogenesis of Parkinson’s Disease.

Questions
1. Could you tell us about the association between constipation and Parkinson’s disease (PD)? (0:06)
2. Could you give us an overview of the evidence supporting the hypothesis that α-synuclein pathology originates in the gut and spreads to the enteric nervous system? (0:33)
3. What have these findings taught us about the cause of PD? (1:16)
4. Could you give us an overview of the key scientific data supporting a role of the gut microbiome in the development of PD? (2:15)
5. How can these findings potentially be used to improve treatment? (3:20)

Disclosures: Prof. Reichmann has no financial or non-financial relationships or activities to declare in relation to this video interview.

Support: Interview and filming supported by Touch Medical Media.

Filmed as a highlight of the International Parkinson and Movement Disorder Society MDS Virtual Congress 2020.

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