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Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare, autoimmune neurological disorder in which peripheral nerve demyelination typically results in weakness, impaired limb sensation, fatigue and pain.1–4 CIDP may adversely affect activities of daily living, with a substantial impact on functional ability and psychological well-being.2–6 Primary treatment goals are reducing symptoms, improving functional status and maintaining long-term remission.7 The […]

Rebecca Gilbert AAN, 2021: Update on Clinical Trials in Parkinson’s and Huntington’s Diseases

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Published Online: May 27th 2021

We were pleased to meet with one of our valued Editorial Board Members, Rebecca Gilbert, MD, PhD (American Parkinson Disease Association, Staten Island, NY, USA) to discuss highlights from the AAN session entitled ‘Update on Clinical Trials in Parkinson’s and Huntington’s Diseases’ presented at the American Academy of Neurology Virtual Annual Meeting 2021.

Questions:

  1. In terms of disease-modifying interventions in Parkinson’s disease (PD), what have been the most exciting clinical trial findings in the last year? (0:15)
  2. What criteria should be used to identify patients who may benefit most from PD disease modifying interventions? (4:05)
  3. Could you give us a brief overview of recently completed and on-going clinical trials in Huntington’s disease? (5:52)
  4. Following the recent decision to discontinue dosing in the Phase III GENERATION HD1 study of tominersen in HD, what does the future hold for huntington-lowering as a potential treatment approach? (8:04)

Disclosures: Rebecca Gilbert has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview was conducted by Katey Gabrysch. Filmed as a highlight of AAN Annual Virtual Meeting 2021

Filmed as a highlight of AAN Annual Virtual Meeting 2021.

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