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Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

Stephen Pasternak, AD/PD 2021: Ambroxol as a Disease-modifying Treatment for Parkinson’s Disease Dementia

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Published Online: Apr 7th 2021

It was a great pleasure to speak with Stephen Pasternak (University of Western Ontario, Ontario, Canada) to discuss ambroxol as a disease-modifying treatment for Parkinson’s Disease dementia.

The abstract entitled ‘Ambroxol as a Disease-modifying Treatment for Parkinson’s Disease Dementia: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial’ was presented at The 15th International Conference for Alzheimer’s & Parkinson’s Diseases (Virtual), March 8-14, 2021.

Question: What is ambroxol and what is the rationale for its use in the treatment of Parkinson’s Disease dementia? (0:14)

Disclosures: Stephen Pasternak has received consulting fees from Zywie Bio LLC.

Support: Interview and filming supported by Touch Medical Media.

Filmed as a highlight of AD/PD Virtual 2021.

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