α-Synuclein conformations are discussed as potentially novel blood biomarkers in Parkinson’s disease (PD). Dr Tim Bartels (UK Dementia Research Institute, University College London, London, UK) joins touchNEUROLOGY to discuss an ultrasensitive assay with antibodies directed against α-Synuclein multimers in blood, which may help to detect slight and early changes in this possible novel PD biomarker.
The abstract entitled: ‘α-Synuclein Conformations as Novel Biomarkers in Blood of PD Patients‘ was presented at the International Conference of Alzheimer’s and Parkinson’s diseases and related neurological disorders (AD/PD), 13-15 October 2021.
- What is the role of the α-Synuclein protein in Parkinson’s disease (PD)? (0:19)
- What is known about different conformations of the α-Synuclein protein in PD? (1:03)
- What was the objective, methodology and findings of the current study? (2:09)
- What is the potential clinical significance of this novel biomarker, and what future studies are planned? (6:45)
Disclosures: Tim Bartels has nothing to disclose in relation to this video interview.
Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch
Filmed as a highlight of AD/PD 2022.
Share this Video
Related Videos In Parkinson's Disease
Angelo Antonini, EAN 2023: Highlights in Parkinson’s disease
touchNEUROLOGY editorial board member Prof. Angelo Antonini (Padua University Hospital, Italy) provides an overview of his top three most important updates and hot topics from the annual European Academy of Neurology (EAN), July 1–4, 2023, in the field of Parkinson’s disease. He particularly focusses on new insights in early detection of the disease before motor symptoms […]
Highlights from EAN 2023!
Veronica Clark, Parkinson’s Europe: Presidential Update, and the Parkinson’s Manifesto for Europe
The European Parkinson’s Disease Association (EPDA) recently changed its name to Parkinson’s Europe. They are the only European Parkinson’s umbrella organisation and have been working with the global Parkinson’s community for nearly 30 years. As a leading voice for Parkinson’s in Europe, they provide trusted information; advance and share good practices; raise awareness and improve […]
Journal articles and more to your inbox
Get the latest clinical insights from touchNEUROLOGYSign me up!