Epilepsy is one of the most common neurological disorders, affecting around 50 million people worldwide. Advances in epilepsy imaging and treatment (e.g. ablative and neurostimulation procedures, and new antiepileptic drugs) have decreased seizure frequency and severity. Yet unmet needs remain with approximately 30% of people with epilepsy refractory to pharmacotherapies. Novel therapeutic targets include AMPA receptors, potassium channels and synaptic vesicle protein 2A. Ongoing developments and improved understanding of the genetics of epilepsy subtypes may provide patient-specific solutions.
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In this episode, we explore the future of continuing medical education (CME) with the team behind touchIME. Hannah Fisher and Matthew Goodwin share insights into global and US trends, the importance of patient inclusivity and how educational outcomes are evolving to better measure the direct impact of learning on clinical practice and patient care.
Seizures are one of the most frequent neurological disorders in neonates − the incidence of seizures in infants born at term is 1–3 per 1,000 live births, and is even higher in both preterm and very-low-birth-weight infants at 1–13 per 1,000 live births.1 Seizures may ...
In this episode, we’re joined by Bradley Love, Professor of Cognitive and Decision Sciences at UCL, ELLIS fellow, and creator of BrainGPT. We discuss how this large language model is poised to assist researchers in advancing their work.
A new guideline has been issued to assist neurologists and clinicians in selecting the best anti-seizure medications for people with epilepsy who may become pregnant. Published in Neurology, the guideline is a collaboration between the American Academy of Neurology (AAN), the American Epilepsy Society (AES) and the Society for Maternal-Fetal Medicine (SMFM), with endorsement from the Child Neurology Society. It updates parts of the 2009 AAN and AES guidelines regarding birth malformations and child development in children born to people with epilepsy.
We're excited to launch a new series of expert Q&As with our editorial board, highlighting their career milestones, top advice, and future insights in their specialties. In this first interview we are honoured to welcome Dr Ruben I Kuzniecky, MD, an internationally recognized leader in epilepsy, epilepsy surgery and neuroimaging.
Affecting over 70 million patients worldwide, epilepsy is a chronic neurological disorder characterized by intermittent bursts of hyper-synchronous neuronal discharges.1Â The manifestations are variable but reflective of the unique milieu and biology of epileptogenic foci.2Â Pharmacological treatment with antiepileptic drugs (AEDs) ...
Rescue medications are an important part of the treatment regimen for patients with intractable epilepsy, specifically those who experience seizure clusters or prolonged seizure episodes. Rescue medications are prescribed to end seizure activity quickly and effectively in order to prevent ...
MDT specialists and a caregiver of a patient with tuberous sclerosis complex (TSC) discuss current and emerging management strategies for TSC-associated seizures.
The surge in social media use seems to have become a sign of our times. Social media has ramified into not only our personal lives but, importantly, also our professional lives and will continue to do so in the future.1–4 ...
Despite the use of various concurrent antiseizure medications (ASMs), over 30% of patients with focal onset seizures have persistent, uncontrolled seizures.1 Hence, the search for new ASMs with better efficacy and tolerability is continuing. Voltage-gated potassium ion channels (Kv) repolarize neuronal ...
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