An Introduction to Epilepsy
Epilepsy is one of the most common neurological disorders, affecting around 50 million people worldwide. Advances in epilepsy imaging and treatment (e.g. ablative and neurostimulation procedures, and new antiepileptic drugs) have decreased seizure frequency and severity. Yet unmet needs remain with approximately 30% of people with epilepsy refractory to pharmacotherapies. Novel therapeutic targets include AMPA receptors, potassium channels and synaptic vesicle protein 2A. Ongoing developments and improved understanding of the genetics of epilepsy subtypes may provide patient-specific solutions.
Browse video highlights and short articles from the conference hub, providing insights into the latest updates from major conferences and peer-reviewed articles from our journal touchREVIEWS in Neurology. This is complimented by a range of educational activities developed in collaboration with our leading expert faculty.
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Improving disease screening in Lennox-Gastaut syndrome
Watch four leading experts discuss the Refractory Epilepsy Screening Tool for Lennox-Gastaut syndrome (REST-LGS) and its diagnostic and treatment implications.
Acute Management of Seizure Clusters and Prolonged Seizures: A Review of Rescue Therapies
touchREVIEWS in Neurology. 2024;20(1):Online ahead of journal publication
Rescue medications are an important part of the treatment regimen for patients with intractable epilepsy, specifically those who experience seizure clusters or prolonged seizure episodes. Rescue medications are prescribed to end seizure activity quickly and effectively in order to prevent further seizure-related morbidities and prevent seizure recurrence. An ideal rescue medication is stable at room […]
Sharing perspectives: Specific DEEs through the lens of a paediatric and an adult neurologist
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The typical patient journey in tuberous sclerosis complex and unmet needs
Sponsored content by Jazz Pharmaceuticals. Watch leading tuberous sclerosis complex (TSC) experts discuss the heterogenous presentation of the disease, typical referral and management pathways and unmet needs.
Highlights from EAN 2023!
Jacqueline French, AAN 2023: XEN1101, a novel potassium channel modulator for the treatment of focal epilepsy
In this interview with touchNEUROLOGY, Prof. Jacqueline French (Comprehensive Epilepsy Center, New York University, New York, NY, US) discusses the needs of adults with focal epilepsy and the mechanisms of action of XEN1101, a novel, potent, selective Kv7.2/7.3 potassium channel. The abstract entitled “XEN1101, a Novel Potassium Channel Modulator: Interim Data From an Ongoing, Long-Term, […]
Jacqueline French, AAN 2023: X-TOLE phase 2b open-label extension trial of XEN1101 in focal epilepsy – interim data
The randomized, double-blind, placebo-controlled phase IIb study X-TOLE (NCT03796962) is investigating the efficacy of XEN1101, a novel potassium channel modulator, in adults with focal epilepsy. In this interview with touchNEUROLOGY, Prof. Jacqueline French (Comprehensive Epilepsy Center, New York University, New York, NY, US) discusses this clinical trial and the outcomes of its open-label extension. The […]
Improving outcomes for patients with tuberous sclerosis complex-associated seizures: Integrating new treatment options into existing care pathways
MDT specialists and a caregiver of a patient with tuberous sclerosis complex (TSC) discuss current and emerging management strategies for TSC-associated seizures.
- Discuss the burden of TSC for patients and caregivers, and explore how TSC-associated seizures are currently managed
- Assess existing and emerging treatment options for TSC-associated seizures including their impact on seizure prevention and delay in onset
- Evaluate to what extent current treatment challenges and knowledge gaps in TSC-associated seizures impact clinical practice
A Bird in the Hand: A Neurologist’s Guide to Efficient Tweeting in the Age of Social Media
touchREVIEWS in Neurology 2022;18(2):76–80 DOI: https://doi.org/10.17925/USN.2022.18.2.76
The surge in social media use seems to have become a sign of our times. Social media has ramified into not only our personal lives but, importantly, also our professional lives and will continue to do so in the future.1–4 At the same time, more neurologists resorted to online learning modalities, including podcasts and social media […]