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Motor neuron synapses with muscle fiber via electrical impulse transmission and neurotransmitter release, forming neuromuscular junctions , motor neuron, neuroscience
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

Neuroimmunology

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An Introduction to Neuroimmunology

Neuroimmunology aims to understand the interactions of the immune and nervous systems. Neural targets involved in many aspects of homeostasis are affected by inflammatory cytokines. The most well-known autoimmune neurological disorder is multiple sclerosis, characterised by an inflammatory autoimmune attack on the myelin sheath and neurodegeneration. Neuroinflammation also plays a role in in Alzheimer’s and Parkinson’s diseases, amyotrophic lateral sclerosis, Huntington’s disease, stroke, chronic depression and schizophrenia. Neuroimmunology is also an important consideration in the design of neural implants. Further understanding of the balance between beneficial and pathological effects of the immune system on the neuronal system will facilitate the development of novel therapies.

Browse our gallery of video highlights and short articles from the conference hub, providing latest expert insights from major conferences and peer-reviewed articles from the journal portfolio.

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What if your medical degree could launch more than a clinical career? In this candid and compelling read, Dr Jon Edelson shares his lessons for early-career clinicians ready to think beyond the bedside and explore the business of medicine.

touchVisionary Voices
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In this episode, we explore the future of continuing medical education (CME) with the team behind touchIME. Hannah Fisher and Matthew Goodwin share insights into global and US trends, the importance of patient inclusivity and how educational outcomes are evolving to better measure the direct impact of learning on clinical practice and patient care.

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 "this is a field where rigorous science can rapidly change lives"   Dr Bardia Nourbakhsh, Associate Professor of Neurology, Johns Hopkins University, Baltimore, MD, USA, is a rising star whose work bridges rigorous clinical neurological research with compassionate, patient-centred care. ...

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Multiple sclerosis (MS) is a chronic neurological condition that often presents with vague or intermittent symptoms, making early recognition particularly challenging in primary care. As diagnostic delays can significantly impact long-term outcomes, timely identification and referral are critical. In alignment ...

12 mins
CE/CME accredited
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touchEXPERT FOCUS
Prof. Xavier Montalban

Join an expert as they discuss MS pathophysiology and the potential of BTK inhibitors to delay progression.

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Brain Awareness Week, taking place from March 10-16, 2025, is a global campaign dedicated to fostering public enthusiasm and support for brain science, organised by the Dana Foundation. Each March, participants worldwide organize imaginative activities that highlight the wonders of the brain and the profound impact of neuroscience on our daily lives.

101 mins
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touchMEETING HIGHLIGHTS
For HCPs in: Global
This content is sponsored by Alexion, AstraZeneca Rare Disease.

Leading experts discuss clinical evidence and real-world experience with complement inhibition therapy in the rare autoimmune disorders AChR-Ab+ gMG and AQP4-Ab+ NMOSD.

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A new study has revealed that early treatment with ocrelizumab significantly reduces disease activity and long-term progression in patients with early-stage relapsing-remitting multiple sclerosis (RRMS).

touchVisionary Voices
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In this episode, we’re joined by Bradley Love, Professor of Cognitive and Decision Sciences at UCL, ELLIS fellow, and creator of BrainGPT. We discuss how this large language model is poised to assist researchers in advancing their work.

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In our latest Q&A, we are delighted to welcome Editorial Board member Dr David Hafler, William S. and Lois Stiles Edgerly Professor and Chairman of the Department of Neurology at Yale School of Medicine, as well as Neurologist-in-Chief at Yale-New Haven Hospital. Dr Hafler's groundbreaking work in multiple sclerosis (MS) research has helped establish the disease as an autoimmune disorder and led to the development of therapies such as natalizumab. His contributions include identifying myelin-reactive T cells, uncovering the genetic and molecular mechanisms underlying MS, and exploring the role of salt in driving autoimmune responses. A highly cited neurologist, he has received numerous awards, including the Dystel Prize, the Raymond Adams Award, and the NIH Javits Investigator Award, and is a member of the National Academy of Medicine.

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The European neuromuscular expert working group has published an updated European consensus on the use of gene therapy for the treatment of spinal muscular atrophy (SMA) .

39 mins
CE/CME accredited
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touchIN CONVERSATION
Prof. John Chen, Prof. Friedemann Paul

A neurologist and a neuro-ophthalmologist discuss best practices for early diagnosis and treatment of NMOSD

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Welcome to the latest edition of touchREVIEWS in Neurology. We are excited to present a collection of articles that showcase the latest advancements and diverse perspectives in neurological research and treatment. This issue features insightful reviews and editorials from esteemed ...

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Patrick Schindler, Friedemann Paul

Neuromyelitis optica spectrum disorders (NMOSD) are a group of relapsing autoimmune diseases of the central nervous system. The clinical hallmarks of NMOSD are myelitis and optic neuritis; however, a wider clinical spectrum has been recognized.1 The majority of patients with ...

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Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory autoimmune disease of the central nervous system (CNS) with a worldwide distribution.1 The first clinical description of NMOSD was made a century ago by Devic and Gault, who documented patients with ...

33 mins
CE/CME accredited
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Prof. Weber shares his expert perspectives on the optimal management of patients with relapsing forms of MS.

36 mins
CE/CME accredited
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touchPANEL DISCUSSION
Prof. Said Beydoun, Dr Pushpa Narayanaswami, Prof. Heinz Wiendl

Watch specialists in neurological disorders share their insights on the role of complement and complement therapeutics in patients with neuromyelitis optica spectrum disorder (NMOSD) and myasthenia gravis (MG).

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