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Joseph Samaha, Jim Dagher, Shayan Abdollah Zadegan

Huntington’s disease (HD) is a neurodegenerative disease inherited in an autosomal dominant manner. It is caused by an expansion of cytosine, adenine, guanine (CAG) repeats within the huntingtin (HTT) gene, which is located on chromosome 4. This pathological expansion of CAG repeats results in the production of a mutant huntingtin protein with an abnormally long polyglutamine […]

Anna Tancin Lambert, EAN 2020 – Atrial Fibrillation and Cryptogenic Stroke in the NOR-FIB Study

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Published Online: Jun 8th 2020

Anna Tancin Lambert (University of Oslo and Department of Neurology Østfold Hospital Trust, Norway) discussed with us exciting interim findings from the international, multicentre, prospective, observational Nordic Atrial Fibrillation and Stroke (NOR-FIB) study, which highlight atrial fibrillation as the hidden cause of cryptogenic stroke (ClinicalTrials.gov Identifier: NCT02937077).

Questions
1. What proportion of stroke and transient ischaemic attack cases are classified as cryptogenic? (
0:05)
2. What are the current recommendations for secondary prevention of cryptogenic stroke? (
0:35)
3. Could you tell us a little about the aims and design of the NOR-FIB study? (
1:05)
4. What have been the interim findings of this study? (
1:42)
5. What changes would you like to see in the guidelines for stroke screening for underlying causes? (
2:53)

Speaker disclosure: Anna Tancin Lambert reports that the study devices were partly funded by Medtronic.

Support: Interview and filming supported by Touch Medical Media.

Filmed at the 6th Congress of the European Academy of Neurology (EAN) and 1st EAN Virtual Congress, May 2020.

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