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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

Daniel Hanley, AAN 2019 – MISTIE III study insights

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Published Online: May 29th 2019

US Neurology Editorial Board member, Daniel Hanley (Johns Hopkins Medicine, Baltimore, Maryland, USA), provides his positive insights on MISTIE III, a clinical trial investigating the efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral hemorrhage evacuation, which failed to meet its primary endpoint of improved functional outcome at 1 year.

 

Questions
1. Could you tell us a little about the MISTIE procedure for the surgical removal of spontaneous intracerebral hemorrhage? (0:04)
2. What were the findings of the MISTIE III study? (1:14)
3. What lessons have been learned from MISTIE III and what will be the next steps in this research (3:12)
4. What are your hopes for the future of this research? (4:52)

 

Speaker disclosures: Daniel Hanley has nothing to disclose in relation to this video interview.

 

Filmed at the American Academy of Neurology (AAN) Annual Meeting, Philadelphia, USA, May 2019.

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