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Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of both upper and lower motor neurons, which ultimately leads to muscle weakness, atrophy, spasticity and contractures.1 ALS typically manifests in the 50–60 years age range, although familial cases may present in late adolescence or early adulthood.2 The time from the first symptom to diagnosis is approximately 10–16 […]

Masatoshi Koga & Manabu Inoue, ESOC 2019 – THAWS trial

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Published Online: Jun 13th 2019

Trial investigators Masatoshi Koga and Manabu Inoue discuss results from THAWS (NCT02002325), an investigator-initiated Japanese multicentre randomised controlled clinical trial designed to clarify the efficacy and safety of MRI-based intravenous thrombolysis with alteplase for patients with acute wake-up ischaemic stroke and those having acute ischaemic stroke with unknown time of symptom onset.

Content produced in Milan, Italy and shared with kind authorisation of the European Stroke Organisation (ESO) and the European Stroke Organisation Conference (ESOC 2019). 

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