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Joseph Samaha, Jim Dagher, Shayan Abdollah Zadegan

Huntington’s disease (HD) is a neurodegenerative disease inherited in an autosomal dominant manner. It is caused by an expansion of cytosine, adenine, guanine (CAG) repeats within the huntingtin (HTT) gene, which is located on chromosome 4. This pathological expansion of CAG repeats results in the production of a mutant huntingtin protein with an abnormally long polyglutamine […]

Vida Demarin, CONy 2020 – Statins for Stroke Prevention in Older Generations

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Published Online: Dec 18th 2020

Vida Demarin (International Institute for Brain Health, Zagreb, Croatia) kindly took the time to speak with us on the topic of the debate session she participated in: Should statins be given to people over age 80 for stroke prevention? As co-Chair of CONy 2021, she also shared her excitement for the next congress, which will be hosted in Dubrovnik, in her home country, Croatia.

Questions

  1. What risks are associated with long-term statin use, and how do these risks change with age? (0:06)
  2. What clinical data are available to assess the benefits and risks of statins in people aged over 80 for stroke prevention? (1:31)
  3. What are the potential issues with extrapolating data from studies involving younger patients? (2:55)
  4. In your opinion, should statins be given to over 80s for stroke prevention? (4:16)
  5. How can we improve our evidence base for this indication? (5:56)

Support: Interview and filming supported by Touch Medical Media Ltd.

Disclosures: Vida Demarin has nothing to disclose in relation to this video.

Filmed in coverage of the 14th World Congress on Controversies in Neurology (CONy Virtual, November 2020).

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