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Motor neuron synapses with muscle fiber via electrical impulse transmission and neurotransmitter release, forming neuromuscular junctions , motor neuron, neuroscience
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper and lower motor neurons that results in progressive motor impairment. ALS is the most common disease of motor neurons with an annual incidence of approximately 1.7–2.5 per 100,000 people. It is a terminal condition with a typical life expectancy of 2–5 years from symptom onset. […]

Can neuroimaging aid in the diagnosis of movement disorders and dementia?

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Published Online: Feb 14th 2015

In a pooled analysis presented at the 2014 AAN Annual Meeting, DaTscan imaging yielded a 91-percent sensitivity rate and a 92-percent specificity rate in diagnosing parkinsonian syndrome; and a 78-percent sensitivity and 90-percent specificity for differentiating dementia with Lewy bodies from Alzheimer’s disease.

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