It was an absolute pleasure to meet with Angela Vincent, Emeritus Professor of Neuroimmunology at the University of Oxford. Until 2016 she led the clinical and research laboratory at Oxford specialising in antibody-mediated neurological diseases. Despite not being a neurologist herself, she spoke from long experience of helping to identify and characterise pathogenic antibodies in patients with movement and other disorders. The views expressed are her own.
Questions
1. What are the major challenges in the diagnosis and treatment of autoimmune movement disorders? (0:05)
2. What are the most common clinical presentations of autoimmune movement disorders? (2:47)
3. How have recent advances helped us understand the molecular mechanisms underlying autoimmune movement disorders? (4:07)
4. Which are the most important neuronal autoantibodies in terms of diagnosis and prognosis? (7:10)
Speaker disclosure: Angela Vincent receives a proportion of royalties from Euroimmun AG for LGI1 and CASPR2 antibody assays.
Filmed at the International Congress of Parkinson’s Disease and Movement Disorders (MDS), Nice, France, September 2019.
